Johns Hopkins University Whiting School of Engineering

Jeff Wang


Associate Professor
Mechanical Engineering
Secondary Appointment: Biomedical Engineering, Sidney Kimmel Comprehensive Cancer Center
http://www.me.jhu.edu/thwang/ (lab)

Latrobe 108 (office)
410-516-7086 ()
thwang@jhu.edu (primary)

Education

Ph.D. 2002, University of California, Los Angeles
M.S. 1994, National Taiwan University
B.S. 1992, National Taiwan University

Experience

1998-2002: Research Assistant, University of California, Los Angeles
1996-1998: Manufacturing Engineer, Taiwan Semiconductor Manufacturing Company (TSMC)
1994-1996: Second Lieutenant, Marine Army, Taiwan, R.O.C.

Research Areas

Single Molecule Manipulation and Detection
Nano/Micro Scale Fabrication
Conformational Dynamics of Biomolecules
BioMEMS and Microfluidics

Journal Articles

Zhang, Y., Liu, K.J., Wang, T.L., Shih, I.M, Wang, T.H. (2012). Mapping DNA Quantity into Electrophoretic Mobility through Quantum Dot Nanotethers for High-Resolution Genetic and Epigenetic Analysis.. ACS Nano. 6(1). 858-64.
DOI »
Zhang, Y., Wang, T.H. (2011). Quantum dots-enabled high-resolution analysis of gene copy number variation: Electrophoretic migration and band broadening of QD-DNA nanocomplex. IEEE Nanotechnology Magazine. 5(2). 23-27.
Zhang, Y., Wang, T.H. (2011). Micro magnetic gyromixer for speeding up reactions in droplets. Microfluidics and Nanofluidics. 1-8.
Park, S., Zhang, Y., Wang, T.H., Yang, S. (2011). Continuous dielectrophoretic bacterial separation and concentration from physiological media of high conductivity. Lab on a Chip - Miniaturisation for Chemistry and Biology. 11(17). 2893-2900.
Zhang, Y., Park, S., Liu, K., Tsuan, J., Yang, S., Wang, T. (2011). A surface topography assisted droplet manipulation platform for biomarker detection and pathogen identification. Lab on a Chip. 11(3). 398-406.
DOI » View record in Web of Science SM

Conference Proceedings

Zhang, Y., Wang, T.H. "An active gyroscopic magnetic micromixer for rapid fluid mixing in droplet based microfluidic systems", 2011, pp.1769-1772.
Zhang, Y., Shin, D.J., Wang, T.H. "Detecting Genetic Variations in a Droplet", 15th International Conference on Miniaturized Chemical and Biochemical Analysis Systems (micro-TAS 2011), 2011, pp.1179-1181.
Zhang, Y., Park, S., Yang, S., Wang, T.H. "Fully integraed droplet based point-of-care platform for molecular detection from crude biosamples", 2011, pp.1927-1930.
Rane, T.D., Zec, H., Puleo, C.M., Lee, A.P., Wang, T.H. "High-Throughput Single-Cell Pathogen Detection on a Droplet Microfluidic Platform", Proceesings: 23rd IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2011), 2011, pp.881-884.
 View record in Web of Science SM
Stark, A., Zhang, Y., Bailey, V., Keeley, B., Wang, T.H. "Increasing throughput and sensitivity of DNA Methylation analysis through functional nanoparticles", 2011, pp.1048-1051.

Awards & Honors

2011 - 2011: Best Paper Award, The 6th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2011)
2011 - 2011: NIST/ Lab on a Chip Art in Science Award - micro-TAS 2011, awarded to Wang’s graduate student Yi Zhang
2011 - 2011: Best Poster Award – 5th Annual INBT NanoBio Symposium
2010 - 2011: Siebel Scholar Award awarded to Wang's graduate student Kelvin Liu
2006 - 2011: CAREER Award, National Science Foundatiom
2010 - 2010: American Association for Cancer Research (AACR) Scholar-in-Training Award awarded to Wang’s graduate student Yi Zhang
2010 - 2010: Best Poster Award, 4th Johns Hopkins NanoBio Symposium
2009 - 2010: Siebel Scholar Award awarded to Wang's graduate student Vas Bailey
2009 - 2009: Best Poster Award, 3rd Johns Hopkins NanoBio Symposium
2009 - 2009: Johns Hopkins University Provost's Undergraduate Research Award (PURA) awarded to Wang’s undergraduate student Brian Keeley
2007 - 2007: CRS Jorge Heller Award - Journal of Controlled Release Oustanding Paper Award
2007 - 2007: Co-author and Faculty Advisor to Hunter Chen, winner of Excellence in Research Award, American Society of Gene Therapy
2004 - 2004: Johns Hopkins University Provost's Undergraduate Research Award (PURA) awarded to Wang's undergraduate student Marcos Kuroki
2003 - 2003: Johns Hopkins University Provost's Undergraduate Research Award (PURA) awarded to Wang's undergraduate student Eric Simone
2002 - 2002: Best Paper/Travel Award, the First World Congress for Chinese Biomedical Engineers, held in Taipei, Taiwan

Presentations

MF3 Industrial Advisory Board (IAB) Meeting / DARPA NEMS/MEMS S&T Fundamentals PI Meeting, Arlington, VA, December 8, 2011
NCI Innovative Molecular Analysis Technologies Program,12th Principal Investigators Meeting, Bethesda, MD, November 14, 2011
The 5th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2011), Jeju Island, Korea, November 9, 2011
DuPont Pioneer Hi-Bred Seminar Series, Johnston, Iowa, October 31, 2011
Mechanical Engineering Department, Johns Hopkins University, Baltimore, MD, October 20, 2011
The 15th International Conference on Miniaturized Chemical and Biochemical Analysis Systems (micro-TAS 2010), Seattle, Washington, October 4, 2011
NCI Alliance for Nanotechnology in Cancer Annual Principal Investigators’ Meeting, Boston, MA, September 20, 2011
The 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC ’11), Boston, MA (Presented by postdoc K. Liu), September 3, 2011
Cancer Detection and Diagnostics Technologies for Global Health, Rockville, Maryland, August 22, 2011
The First Annual EITC Young Investigator Conference, Cambridge, MA, August 18, 2011
The 16th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2011), Beijing, China (Presented by student Y. Zhang), June 6, 2011
SPIE Defense, Security and Sensing Conference, Orlando, FL, April 27, 2011
Monsanto Chemistry Seminar Series, St. Louis, MO, April 19, 2011
SLAS Lab Automation Conference and Exhibition (Lab Automation 2011), Palm Springs, CA, February 1, 2011
The Lab Automation Conference and Exhibition (Lab Automation 2011), February 1, 2011
The 6th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS), Kaohsiung, Taiwan, January 21, 2011
MF3 Industrial Advisory Board (IAB) Meeting  / DARPA NEMS/MEMS S&T Fundamentals PI Meeting, December 14, 2010
2010 IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2010), Hong Kong, December 6, 2010
NIH/NIAID Middle Atlantic Regional Center of Excellence (MARCE) PI meeting, November 15, 2010
2010 Biomaterials Day Symposium, Baltimore, MD, October 29, 2010
14th International Conference on Miniaturized Chemical and Biochemical Analysis Systems (micro-TAS 2010), Groningen, Netherlands(Presented by student C. Beh & Y. Zhang), October 3, 2010
2nd Johns Hopkins Ovarian Cancer Symposium: Early Carcinogenesis, Cancer Genomics & Biology, Baltimore, MD, September 30, 2010
2010 Gordon Conference on Bioanalytical Sensors, New London, NH, June 22, 2010
NIH/NIAID Middle Atlantic Regional Center of Excellence (MARCE) PI meeting, June 2, 2010
Fischell Department of Bioengineering, University of Maryland, College Park,  MD, April 23, 2010
6th National RCE Meeting, Las Vegas, Nevada, April 12, 2010
23rd IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS2010), Hong Kong (Presented by student Y. Zhang), January 24, 2010
Integrating Micro- and Nano-Technologies for Analysis of Biomolecules Cell Biophysics Symposium, School of Medicine. Baltimore, Maryland. 2008-11-24. (Invited), November 24, 2008
Nanobiosensing Method for Molecular Analysis of Cancer NIH NCI Innovative Molecular Analysis Technologies (IMAT) Program PI meeting. Boston. Massachusetts. 2008-10-28., October 28, 2008
Microfluidic, Free-Standing Corneal Epithelium through Enzymatic Etching within Hybrid PDMS-Collagen Devices Biomedical Engineering Society Annual Meeting. St. Louis, Missouri. 2008-10-03., October 3, 2008
Micro/Nanotechnology for Ultrasensitive and High-throughput Biomolecular Analysis Pathology Grand Rounds, Johns Hopkins School of Medicine. Baltimore. Maryland. 2008-09-18. (Invited), September 18, 2008
Microfluidic Single-Molecule Platform for Ultrasensitive Detection Symposium Toward a Strategic Vision for Basic Sciences for Chemical and Biological Defense. Atlanta, Georgia. 2008-08-07. (Invited), August 7, 2008
E. Coli Detection in Picoliter Droplets using Confocal Fluorescence Detection MF3 Industrial Advisory Board (IAB) Meeting. Irvine, California. 2008-08-06., August 6, 2008
Quantum Dots For Molecular Analysis of Cancers NanoBio Symposium 2008, Institute for NanoBiotechnology & The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine. Baltimore, Maryland. 2008-05-01. (Invited), May 1, 2008
Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Departmental Seminar, Department of Aerospace and Mechanical Engineering, University of Arizona. Tucson, Arizona. 2008-04-10. (Invited), April 10, 2008
Ultratrace Detection of Explosives Enabled by an Integrated Microfluidic Nanosensing System NSF/DHS S&T Explosives and Related Threats: Frontiers in Prediction and Detection (EXP) Grantees Conference. Arlington, Virginia. 2008-01-17., January 17, 2008
Quantitative Kinetic Analysis of DNA Nanocomplex Self-Assembly with Quantum Dots FRET in a Microfluidic Device 21st IEEE International Conference on Micro Electro Mechanical Systems. . 2008-01-14., January 14, 2008
E. Coli Detection in Picoliter Droplets Using Confocal Fluorescence Detection MF3 Industrial Advisory Board (IAB) Meeting / DARPA NEMS/MEMS S&T Fundamentals PI Meeting. Napa Valley, California. 2008-01-13., January 13, 2008
Quantitative Confocal Spectroscopy – Rectifying the Limitations of Single Molecule Detection The 3rd Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS). Sanya, Hainan, China. 2008-01-00. (Invited), December 31, 2007
Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Seminar: Department of Mechanical Engineering and Mechanics, Drexel University. Philadelphia, Pennsylvania. 2007-11-00. (Invited), October 31, 2007
Integrating Micro- and Nano-Technologies for Analysis of Biomolecules Division Seminar: Department of Oncology, Johns Hopkins Medical Institute. Baltimore, Maryland. 2007-09-00. (Invited), August 31, 2007
Quantum Dots-FRET-Based Nanosensors for Point Mutation Detection HUGO IX International Symposium on Mutation in The Genome (2007 Mutation Detection). Xiamen, China. 2007-09-00. (Invited), August 31, 2007
Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors The Symposium: Nano Meets Micro, Center of Advanced Learning in Information Technologies (CALIT), IMEC. Leuven, Belgium. 2007-09-00. (Invited), August 31, 2007
QD-FRET Detection of E-coli in Microfluidic Droplets MF3 Industrial Advisory Board (IAB) Meeting / DARPA NEMS/MEMS S&T Fundamentals PI Meeting. San Francisco, California. 2007-06-00. (Invited), May 31, 2007
Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Bureau of Forensic Services, Department of Justice, Sate of California. Richmond, California. 2007-06-00. (Invited), May 31, 2007
Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Fifth International Conference on Nanochannels, Microchannels and Minichannels (ASME ICNMM 2007). Puebla, Mexico . 2007-06-00. (Invited), May 31, 2007
Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Department of Electrical and Computer Engineering, University of Maryland, College Park. Maryland. 2007-03-00. (Invited), February 28, 2007
Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Divisional Research Seminars in the Division of Gynecological Pathology, Johns Hopkins Medical Institute. Baltimore, Maryland. 2006-11-14. (Invited), November 14, 2006
Pushing The Sensitivity of Nanoscale Biosensing Systems to The Fundamental Limit PI Meeting, DARPA N/MEMS Science and Technology Fundamentals / Micro/Nano Fluidics Fundamentals Focus (MF3) Center. Minneapolis, Minnesota. 2006-10-26. (Invited), October 26, 2006
Integrating single-molecule detection, quantum dot nanosensors, and microfluidic manipulations for analysis of low-abundance biomolecules The 2nd American Academy of Nanomedicine Annual Meeting. Washington DC. 2006-09-09. (Invited), September 9, 2006
Single Molecule Quantitative Detection and Analysis of Low-Abundance Biomolecules The Symposium: Mining the Biology-Physics Interface, Biology Department, Johns Hopkins University. Baltimore, Maryland. 2006-01-25. (Invited), January 25, 2006
Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Biomedical Engineering Department, University of California, Irvine. Irvine, California. 2006-01-12. (Invited), January 12, 2006
Integrative Innovations in Nanotechnologies, Single-Molecule Detection and Microlfuidics for Sensing & Quantification of Biomolecules . Howard Hughes Medical Institute, Johns Hopkins Medical School. 2005-11-23., November 23, 2005
Integrating Microfluidic Manipulations and Single-Molecule Detection for Quantitative Analysis of Biomolecules on a Chip 6th Annual CAMD/CBM2 Summer Workshop. Barton Rouge, LA. 2005-07-25. (Invited), July 25, 2005
Point Mutation Detection with Quantum Dot Nanosensor International Conference on Bio-Nano-Information Fusion. Marina DelRay, California. 2005-07-21., July 21, 2005
Quantitative Detection of Biomolecules with Microfluidic Manipulations and Single-molecule Detection The Chinese Biopharmaceutical Association (CBA) Annual Conference. Rockville, Maryland. 2005-06-19. (Invited), June 19, 2005
Integrative Innovations in Nanotechnologies, Single-Molecule Detection and Microlfuidics for Sensing & Quantification of Biomolecules . Pathology Department, Johns Hopkins Medical School . 2005-01-14., January 14, 2005
Micro/Nano Technologies for Single-Molecule Detection NioMEMS and Nanotech World 2004. Washington, D.C.. 2004-08-18. (Invited), August 18, 2004
Ultrasensitive Quantitative Analysis of Biomolecules Using Single-molecule Detection and Micro Fluidic Devices Invited talk at Peking University. Beijing, China . 2004-05-24. (Invited), May 24, 2004
Ultrasensitive Quantitative Analysis of Biomolecules Using SIngle-molecule Detection and Micro FLuidic Devices Invited Talk at Shanghai Jaio Tong University. Shanghai, China. 2004-05-21. (Invited), May 21, 2004
Ultrasensitive Genomic Analysis Using Single-molecule Detection, Micro Fluidic Chips, and Nanoparticle Molecular Probes The First U.S. -China Nanotechnology Forum. Beijing, China. 2004-05-17. (Invited), May 17, 2004
Ultrasensitive Bio-Detection with Quantum Dot-based Nano Biosensors Invited Talk at Sensors and Electron Devices Directorate, Army Research Laboratory. Army Research Laboratory . 2004-02-24. (Invited), February 24, 2004
Specific Single-Biomolecule Detection Mechanical Engineering Departmental Seminar, Johns Hopkins University. Baltimore, MD. 2003-10-23., October 23, 2003
Nano/Micro Technologies for Single Molecule Manipulation and Detection 2003 IEEE International Conference on Robotics and Automation . Taipei, Taiwan. 2003-09-17. (Invited), September 17, 2003
Specific Single-Biomolecule Detection Using Fluorescence Correlation Spectroscopy and Quantum-dot Probes Invited Talk in the Biomedical Engineering Department at University of Southern California . Los Angeles, California. 2003-09-07., September 7, 2003
Specific Single-Biomolecule Detection Using Fluorescence Correlation Spectroscopy and Quantum-dot Probes Invited Talk at the Center for Cell Mimetic Space Exploration (CMISE) at University of California, Los Angeles. Los Angeles, California. 2003-09-05., September 5, 2003
BioMEMS for Single Molecule Manipulation and Detection 2003 BioMEMS Conference. San Jose, Claifornia. 2003-06-17. (Invited), June 17, 2003
BioMEMS Devices for Control and Manipulation of Single Molecules CISSTS ERC (Engineering Research Center for Computer-Integrated Surgical Systems and Technology ) Seminar . . 2003-04-09. (Invited), April 9, 2003
Nano/Micro Technology for Detecting a Single DNA Molecule 2002 World Congress for Chinese Biomedical Engineer (WCCBME2002). Taipei, Taiwan. 2002-12-11., December 11, 2002
High Throughput, Quantitative DNA Methylation Screening Using a Quantum Dot Based Nanotechnology Assay 2. AACR Molecular Diagnostics in Cancer Therapeutic Development conference: Fulfilling the Promise of Personalized Medicine,. Philadelphia, Pennsylvania, . 0000-00-00., November 30, 1999
Single-Molecule Quantitative Detection and Analysis of Low-Abundance Biomolecules The Symposium: Mining the Biology-Physics Interface, Biology Department, Johns Hopkins University. Baltimore, Maryland. 0000-00-00., November 30, 1999

Committees

2007: ME Undergraduate Program and Student Affairs Committee, Mechanical Engineering Department, JHU
2006: Technical Committee, IEEE Nanotechnology Council for Nanosensors and Nanoactuators
2004: Biomechanics Committee, Mechanical Engineering Department, Johns Hopkins University
2003: Whitaker Institute Lithography and Fabrication Facility Committee, 2003-
2011: Whiting School of Engineering Safety Committee
2011: KSAS/WSE Faculty Admissions Technology Work Group
2011: JHU ME Biomechanics Faculty Search Committee
2011: Technical Program Committee: The 7th Annual IEEE International Conference on Nano/Micro Engineering and Molecular Systems (IEEE NEMS)
2011: Organizing Chair: 6th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2012)
2010 - 2011: Technical Program Committee: The 19th IFIP/IEEE International Conference on Very Large Scale Integration (VLSI-SoC), 2011
2010 - 2011: Technical Program Committee: The 6th Annual IEEE International Conference on Nano/Micro Engineering and Molecular Systems (IEEE NEMS), 2011
2010 - 2011: Lecturer Search Committee, Mechanical Engineering, JHU
2010 - 2011: Biomechanics Faculty Search Committee, Mechanical Engineering, JHU
2010 - 2011: Steering Committee: The First Annual EITC Young Investigator Conference (EITCV-YIC 2011)
2010 - 2011: Program Co-Chair: 5th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2011)
2007 - 2010: ME Seminar Series and Course Committee,Mechanical Engineering Department, JHU
2007 - 2010: Advisor for the Mechanical Engineering Undergraduate Student Council, JHU
2006 - 2006: Technical Program Committee: The 7th IEEE International Conference on Nanotechnology (IEEE NANO-2007), Aug 2-4, 2007, Hong Kong 
2005 - 2006: Technical Program Committee. The First Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2006)
2005 - 2006: Engineering Mechanics Undergraduate Curriculum Committee, Mechainal Engineering Department, Johns Hopkins University